DOES OBESITY CAUSE DIABETES TYPE 2?

DOES OBESITY CAUSE DIABETES TYPE 2?

Type 2 diabetes is a complex metabolic disorder that can be influenced by various factors, including genetics, lifestyle, and environmental factors. While obesity is a significant risk factor for type 2 diabetes, it is not the sole cause of the disease. Instead, obesity is one of several factors that can contribute to the development of type 2 diabetes. 

☝️Almost 90% of people with type 2 diabetes are overweight or obese.

👆Recent studies suggest obese people are up to 80 times more likely to develop type 2 diabetes than people with a normal BMI.

Here's how obesity and other factors are related to type 2 diabetes:

Obesity and Insulin Resistance:

  • Obesity, particularly excess abdominal fat (visceral fat), is strongly associated with insulin resistance, a condition in which the body's cells become less responsive to insulin, a hormone that regulates blood sugar levels.
  • Insulin resistance leads to higher levels of insulin in the bloodstream (hyperinsulinemia) as the body attempts to compensate for the reduced effectiveness of insulin. Over time, this can contribute to the development of type 2 diabetes.

Adipose Tissue Inflammation:

  • Adipose tissue (fat tissue) in obese individuals can become inflamed, releasing inflammatory molecules (adipokines) and contributing to systemic inflammation and insulin resistance.
  • Chronic low-grade inflammation associated with obesity can impair insulin signaling and glucose metabolism, increasing the risk of type 2 diabetes.

Genetic Factors:

  • Genetic predisposition plays a significant role in the development of type 2 diabetes. Certain genetic variants can influence an individual's susceptibility to insulin resistance, impaired glucose metabolism, and obesity.
  • Individuals with a family history of type 2 diabetes have an increased risk of developing the condition, regardless of their weight status.

Lifestyle Factors:

  • Sedentary lifestyle, poor dietary habits, and unhealthy behaviors such as smoking and excessive alcohol consumption can contribute to obesity and increase the risk of type 2 diabetes.
  • Regular physical activity, a balanced diet, weight management, and other healthy lifestyle choices can help reduce the risk of developing type 2 diabetes, even in individuals who are overweight or obese.

Other Risk Factors:

  • Other risk factors for type 2 diabetes include advancing age, ethnicity (certain racial and ethnic groups are at higher risk), gestational diabetes during pregnancy, polycystic ovary syndrome (PCOS), and certain medical conditions (such as hypertension and dyslipidemia).

     

Type 2 diabetes can develop slowly. Untreated type 2 diabetes can lead to a range of serious complications, such as –
🔹High blood sugar and tissue damage throughout your body;
🔹Slow-healing cuts or sores;
🔹Gum infections and disease;
🔹Vision problems, higher risk of cataracts, glaucoma, eye infections; diabetic retinopathy;

🔹Nerve damage, called neuropathy, that can cause pain or numbness in your hands and feet;
🔹Heart disease;
🔹High blood pressure;
🔹Circulatory problems;
🔹Kidney problems.

Overall, bariatric surgery can be an effective tool for treating type 2 diabetes, leading to significant improvements in glycemic control, reduction in diabetes-related complications, and improvement in overall health and quality of life. 80-90% of diabetic bariatric surgery patients achieve a long-term disease improvement or resolution after the bariatric surgery. This improvement is often observed shortly after surgery, before even significant weight loss occurs.